Detailed Mechanism Funding and Narrative

Years of mechanism: 2013 2014 2015

Details for Mechanism ID: 16759
Country/Region: South Africa
Year: 2013
Main Partner: Columbia University
Main Partner Program: Mailman School of Public Health
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $600,000

The Paediatric Enhanced Surveillance Survey (PESS) proposes to routinely follow 500 children already on ART and 300 children who are newly initiated on ART in the Eastern Cape province. The children will be followed in term of clinical, immunologic, virological, metabolic, psychosocial and behavioral outcomes from the age of 4 weeks to less than 12 years. The survey has three parts: (1) a comprehensive record review of all HIV-infected children enrolled at five pediatric Wellness and ART clinics; (2) a cross sectional assessment; and (3) a two-year follow-up. The surveillance will be built upon and support the routine clinical care encounters, visit schedule and patient monitoring. As part of the two-year follow-up we will aim to collect information on children lost to follow-up, including causes of death through the review of death certificates in the clinical chart and through verbal autopsy reports. This work is designed in collaboration with the provincial health authorities of the EC, ICAP-SA and CDC-SA in support of the South African National ART Program for Children and aims to collect and analyze accurate, relevant and useful information on the children seen at the five Wellness and ART clinics. It is expected that the survey will provide insights into overall outcomes for the larger pediatric patient populations in the province and South Africa.

Funding for Treatment: Pediatric Treatment (PDTX): $600,000

The Paediatric Enhanced Surveillance Survey (PESS) proposes to routinely follow 500 children already on ART and 300 children who are newly initiated on ART in the Eastern Cape province. The children will be followed in term of clinical, immunologic, virological, metabolic, psychosocial and behavioral outcomes from the age of 4 weeks to less than 12 years. The survey has three parts: (1) a comprehensive record review of all HIV-infected children enrolled at five pediatric Wellness and ART clinics; (2) a cross sectional assessment; and (3) a two-year follow-up. The surveillance will be built upon and support the routine clinical care encounters, visit schedule and patient monitoring. As part of the two-year follow-up we will aim to collect information on children lost to follow-up, including causes of death through the review of death certificates in the clinical chart and through verbal autopsy reports. This work is designed in collaboration with the provincial health authorities of the EC, ICAP-SA and CDC-SA in support of the South African National ART Program for Children and aims to collect and analyze accurate, relevant and useful information on the children seen at the five Wellness and ART clinics. It is expected that the survey will provide insights into overall outcomes for the larger pediatric patient populations in the province and South Africa.